Active substance: Letrozole
Letrozole (Chemical Formula is C₁₇H₁₁N₅) is known to be an aromatase inhibitor that is used to treat hormonally-responsive breast cancer after surgery and, at the same time, works by blocking the production of estrogen. The unwanted effect of this estrogen is that it causes a decrease in good cholesterol in the blood. That is because estrogen is linked with blood cholesterol, and estrogen inhibition reduces good cholesterol in the blood. To be concise, Letrozole is an anti-cancer medication inhibiting estrogen production in post-menopausal women diagnosed with breast cancer and reversibly inhibits its aromatase. In addition to its use in the medical world, Letrozole is used by bodybuilders and athletes seeking to gain an edge in their respective sports by obtaining stronger muscle mass and a striated appearance.
Scientists of the Swiss Company Ciba-Geigy AG, now called Novartis, discovered Letrozole in the 1980s. They described it as among any other aromatase inhibitor, and Letrozole is more potent. In 1996, because of its speedy development, it garnered approval from the U.S. Food and Drug Administration. Letrozole has been in use since the late 1990s and has become a popular treatment for various medical conditions.
Letrozole is identified as a non-steroidal inhibitor of estrogen synthesis which catalyzes the development of estrogen to androgens. Thus, it can be easily drawn out that Letrozole assists in treating cancers that feed off estrogens to stimulate their growth. It also blocks estrogen synthesis in post-menopausal women and is administered in cancer therapies. Additionally, Letrozole does not reduce the creation of corticosteroids in the body. Letrozole has a molecular weight of 285.3 g/mol.
In addition to its medical uses, Letrozole has become popular among bodybuilders and athletes. They use it to reduce estrogen levels in the body, which can help to minimize the side effects of anabolic steroids. It can also help to increase strength, reduce body fat, and improve muscle definition.
Letrozole can offer several potential benefits, depending on the reason it is being used. In the treatment of breast cancer, it can slow down the growth of certain types of cancer. In the treatment of endometriosis, it can reduce the pain and other symptoms associated with the condition. Finally, in the treatment of infertility, it can help to improve ovulation and increase the chances of pregnancy.
In addition to its medical uses, Letrozole can offer many potential benefits for bodybuilders and athletes. Such as:
The most common side effects of Letrozole include the following:
Other less common side effects may include:
Letrozole is typically used during the steroid cycle for estrogen control. It is commonly used at a dosage of 0.5mg to 2.5mg per day. The length of use will depend on individual goals and the steroid cycle being used, but typically it is used for the entire cycle duration. It is important to note that Letrozole should only be used under the supervision of a medical professional.
Always take necessary precautions when taking non-steroidal drugs since the effects may vary in different situations and conditions of patients.
Tell your doctor and pharmacist your medical history and other medications are previously taken so they can guide you or prevent you from allergic reactions to the said drug. Always disclose other prescription and non-prescription medicines, such as vitamins, supplements, or other herbal supplements that may be contraindicated.
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